Methodology development of sample preparation for cryo-EM studies
Project Description
Preparation of high-quality cryo-specimen is critical to achieve high resolution in single particle cryo-EM studies. This project aims to optimize cryo-specimen preparation by introducing chemical materials
Supervisor
DANG, Shangyu
Quota
1
Course type
UROP1100
UROP2100
UROP3100
UROP3200
UROP4100
Applicant's Roles
Explore new approach to optimize traditional plunge freezing.
Evaluate different methods by using Cryo-ET and other EM technique.
Evaluate different methods by using Cryo-ET and other EM technique.
Applicant's Learning Objectives
Basic knowledge of cryo-EM.
Hands-on experience of EM.
Cryo-EM sample preparation.
Cryo-EM data acquisition and processing.
Hands-on experience of EM.
Cryo-EM sample preparation.
Cryo-EM data acquisition and processing.
Complexity of the project
Challenging