CRISPR/Cas9 analysis of essential genes
Project Description
The CRISPR/Cas9 technology has revolutionised the ability to perform gene editing including gene knockout in mammalian cells. Knockout of genes essential for cell growth, however, is not possible using CRISPR/Cas9 alone. This project involves the use of inducible systems to disrupt essential genes and study their functions in cancer cells.
Supervisor
POON Randy Yat Choi
Quota
2
Course type
UROP1000
UROP1100
UROP2100
UROP3100
Applicant's Roles
• Design and conduct experiments
• Analysis and presentation of data
• Analysis and presentation of data
Applicant's Learning Objectives
• Be proficient in techniques in molecular and cell biology
• Develop ability to analyse results and trouble shooting
• Develop team work
• Develop ability to analyse results and trouble shooting
• Develop team work
Complexity of the project
Challenging