Engineering of next generation mRNA vaccine construct
The linear mRNA is the first generation of mRNA vaccines. But it has several limitations, including the short cellular half-life. The aim of this project is to design a long-lasting mRNA construct for high performance mRNA vaccine.
KUANG Becki Yi
RNA design and synthesis; mammalian cell culture; RNA transfection and expression measurement; data processing.
Applicant's Learning Objectives
To learn how to successfully design an artificial RNA with expect functions in cell; to understand the role of each structural elements of an mRNA.
Complexity of the project