Engineering an Orthogonal recombinant glycoconjugate vaccine for protection against enterotoxigenic toxins generated by Escherichia coli
Project Description
Shiga toxin, produced by Enterotoxigenic Escherichia coli (ETEC), is a major virulence factor responsible for severe human diseases. This project aims to employ synthetic biology techniques to engineer an orthogonally glycoconjugate vaccine capable of enhancing the neutralizing effect of an antibody against the lethal enterotoxin.
Supervisor
HSING, I-ming
Quota
2
Course type
UROP1000
UROP1100
UROP2100
UROP3100
UROP3200
UROP4100
Applicant's Roles
1) Demonstrate passion for the project and enthusiasm for conducting experiments.
2) Commit sufficient time and effort to the project throughout the UROP period.
3) Communicate effectively with PhD mentors.
4) Uphold high academic standards and maintain strong ethical integrity in all aspects
2) Commit sufficient time and effort to the project throughout the UROP period.
3) Communicate effectively with PhD mentors.
4) Uphold high academic standards and maintain strong ethical integrity in all aspects
Applicant's Learning Objectives
1) To build a strong foundational knowledge essential for conducting critical and impactful research in biological engineering.
2) To motivate themselves to engage in open-ended, research-driven projects.
3) To explore and better understand their own potential and interests within the realm of research
2) To motivate themselves to engage in open-ended, research-driven projects.
3) To explore and better understand their own potential and interests within the realm of research
Complexity of the project
Challenging