Green Chemistry in Organic Synthesis
The project will use Green Chemistry principles to design and optimize important organic reactions so that the operation risks (toxic and explosive) and chemical waste are minimized or even eliminated. Preparation of organic molecules, a very interesting but challenging process, very often requires employments of toxic and reactive reagents that increase the cost and time and produce hazardous substances. Herein, this project will be focused on new synthetic method development, which is based on Green Chemistry: utilization of a set of principles that reduce or eliminate the use or generation of hazardous chemicals. Specifically, a new synthetic protocol with environmentally friendly reagents is identified, optimized, and finally demonstrated to make medicinally valuable organic molecules. In addition, the project provides trainings of undergraduate students to interpret spectroscopic data at intermediate/advanced level of analytical skills (NMR, TLC, HPLC, column chromatography, and IR). Students enrolled this project are required to take and pass the safety training courses (Chemical Safety I and II).
The applicant will be trained with organic synthesis first and then carry out organic reactions.
Applicant's Learning Objectives
Applicant's learning objectives include learning green chemistry principles, organic reactions, reaction mechanisms, TLC and Column chromatography skills.
Complexity of the project